Abstract In this work blends based on calcium aluminate cement (CAC) containing bioactive glass (BG) (5, 7.5 and 10 wt%) and strontium oxide (1 wt%) were produced aiming improve their bioactivity and the capacity to stimulate the bone regeneration. In the first part, the blends containing only BG were characterized as theoretical density, microhardness, uniaxial cold crush strength after SBF and apparent porosity and pore size distribution before and after SBF treatment. In the second part, bioactivity and cell culture tests were also conducted in the blends containing BG and strontium oxide. The addition of 7.5 wt% of BG in homogeneous calcium aluminate cement (CH) improved its mechanical properties as microhardness and uniaxial cold crushing strength. The blends were more bioactive due to the presence of a highly soluble amorphous phase as confirmed by means of SEM/EDX mainly for 7.5 wt% BG without and with Sr from 1 day in SBF. FTIR analyses indicated the formation the apatite-like phase by means of increase of intensity of the PO43- peaks after SBF treatment. All blends allowed the development of the osteoblastic phenotype and the formation of mineralized matrix increased due to the inclusion of BG and Sr promoting the osteogenesis process.

O objetivo deste experimento foi avaliar, por meio da técnica in vitro semiautomática de produção de gases, a cinética de fermentação dos carboidratos e a degradabilidade da matéria seca (MS) e da orgânica (MO) de dietas contendo níveis de feno de erva-sal (8,4; 18,8; 31,2 e 48,3%) associado à palma forrageira in natura. As leituras de pressão dos gases foram feitas com transdutor de pressão às 2, 4, 6, 8, 10, 12, 14, 17, 20, 24, 28, 34, 48, 72, 96 horas pós-inoculação. A cinética ruminal foi descrita pelos parâmetros: potencial máximo de produção de gases, "lag time" e taxa de produção de gases (k) dos carboidratos fibrosos (CF) e não fibrosos (CNF). Verificou-se que a adição de feno de erva-sal às dietas promoveu efeito quadrático na produção de gases provenientes dos CNF, em que o menor valor observado (136,48mL) foi encontrado com a adição de 38,25% de feno, e o maior valor, com a adição de 8,4% de feno e 74,9% de palma forrageira. O tempo de latência teve comportamento quadrático em função da adição de feno. No entanto não houve efeito significativo na produção de gases provenientes dos CF (média de 111,6mL) e nas taxas de produção de gases dos CNF e CF que apresentaram média de 0,090h-1 e 0,028h-1, respectivamente. A degradabilidade da MS e MO não diferiram em função da adição de feno de erva-sal e apresentaram médias de 85,8 e 90,9%, respectivamente. O uso de 8,4% de feno e 74,9 de palma forrageira propiciou o máximo potencial de produção de gases da fração fibrosa de dietas contendo palma e feno de erva-sal.

The aim of this experiment was to evaluate, by means of the semi-automated in vitro gas production technique, fermentation kinetics of carbohydrates and degradability of dry matter (DM) and organic matter (OM) of diets containing oldman saltbush hay levels (8.4; 18.8; 31.2 and 48.3%) associated to forage cactus in natura. Pressure readings of the gases were done with a pressure transducer at 2, 4, 6, 8, 10, 12, 17, 20, 24, 28, 34, 48, 72 and 96h post-inoculation. The rumen kinetics was described by the following parameters: maximum potential of gas production, lag time and production rates of gas (k), fibrous carbohydrates (FC) and non-fibrous carbohydrates (NFC). It could be observed that the addition of oldman saltbush hay to the diets promoted a quadratic effect in the production of gases originated from NFC. However, there was no significant effect on the production of gases originated from FC and on production rates of gases from NFC and FC. The degradability of DM and OM did not differ due to the addition of oldman saltbush hay. The use of 8.4% hay and 74.9% forage cactus promoted the maximum potential of production of gases from the fibrous fraction of diets containing cactus and oldman saltbush hay.